Weight might be an issue. Are you planning on making the tufa directly on the back glass or are you going to make a tufa background fitted for that area and attach it to the glass? (The former method does have the disadvantage that if you later change your mind and wish to remove it, you likely won't be able to do so.)
Many folks will use an expanding foam like GreatStuff. It has the advantage of being lightweight and can be carved quite easily when is partly (but not fully) cured. After curing, it typically is covered with silicone or grout. Before the silicone has fully cured, it can be covered or impregnated with bark, peat, sand ... whatever will provide the look you are aiming for.
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