I don't know for sure what it is, but I would remove that since it is spreading. Use a sterile blade and cut into green tissue. If you have a fungicide I would treat the plant but at the least dab some cinnamon on the open cut and maybe wipe the remaining plant with some rubbing alcohol. Move it away from other plants. Was water left standing on the leaf at some time? Since it is struggling it is likely more susceptible to infections.