Hormones don't "build up", as they degrade upon exposure to light and warmth. (Also, I have tested KelpMax - the hormone source in Solo - at 100:1 at every watering, and not seen such a reaction.)
If the synthetic hormones (K-L-N, SuperThrive) are applied heavily and frequently, deformation can occur, but is it usually a mangling of the flower, not indications of peloria.