IMHO Barkerias deserve and will eventually see more use in hybridization, especially as some of the relatively newer intergeneric lines progress. Like Broughtonia and Encyclia, Barkeria potentially improves count and proportional size of flowers while miniaturizing habit and improving environmental tolerances. Even the larger, more unruly Barkerias stay fairly compact, and the smaller species are downright miniature compared to the average 'reed-stem' Epidendrum.
I suspect the genus is under-utilized to date mainly because few species are widely cultivated, and because breeding goals have shifted somewhat in the last 20 or 30 years. There's often a lot of lag in orchid hybridizing because of the time and resources required to raise successive generations from seed, and uncertain future economic conditions tend to make breeders warier of unproven intergeneric combinations. I'd wager that within my (hopefully long) lifetime, Barkeria spp. will eventually be ancestor to at least as many popular/important hybrids as Brassavola spp., though.
Allen Black is a hobby breeder who's made some interesting and lovely novel intergenerics, most involving Brassavola but a good few with Barkeria as well. I also know of a few professional breeders dabbling in Bark. intergenerics, though for the time being those efforts are very much a sideline to their main business.