I wouldn't, but I have a zygo that has 75% black-marked leaves ! You only have to worry if the surrounding area gets soft and starts to spread. The leaf is still providing nutrients and by removing it ,you impact the plant. If you are worried about how it looks, then by all means remove it carefully by cutting it off with a scissors.
I am probably going to get people jumping in and saying sterilise the scissors and paint the cut with cinnamon but in nature plants withstand a lot tougher treatment.
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